Muscle Building IGF Peptide IGF-1 DES 1mg/vial Growth Hormone For Weight Loss

Muscle Building IGF Peptide IGF-1 DES 1mg/vial Growth Hormone For Weight Loss

MOQ:10vials (1kit)
Price:Negotiation
PRODUCT DESCRIPTION
High Light:

hgh growth factor

,

igf muscle growth

Brand Name SGH
Certification GMP, ISO9001,BRC,KOSHER
Minimum Order Quantity 10vials (1kit)
Model Number IGF-1 DES
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ABOUT US
Jiangsu Biostronger Technology Co.,Ltd
Jiangsu Biostronger Technology Co.,Ltd manufacturer profile
Hehai Road, Xinbei disctrict, Changzhou, Jiangsu, China ,China
5.0
Verified Supplier
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Muscle Building IGF Peptide IGF-1 DES 1mg/vial Growth Hormone For Weight Loss
Muscle Building IGF Peptide IGF-1 DES 1mg/vial Growth Hormone For Weight Loss
MOQ: 10vials (1kit)
Price:Negotiation
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About Us
Jiangsu Biostronger Technology Co.,Ltd
Jiangsu Biostronger Technology Co.,Ltd manufacturer profile
Hehai Road, Xinbei disctrict, Changzhou, Jiangsu, China ,China
5.0
Verified Supplier
Company Name Jiangsu Biostronger Technology Co.,Ltd
Business Type: Manufacturer
Brands: SGH
No. of Employees: >100
Company Location Hehai Road, Xinbei disctrict, Changzhou, Jiangsu, China
Factory Location Hehai Road, Xinbei disctrict, Changzhou, Jiangsu, China
China Jiangsu Biostronger Technology Co.,Ltd manufacturer profile

Jiangsu Biostronger Technology Co.,Ltd. is one high-tech biological enterprise, established in 2012, our company has been focusing on production and sales of HGH products, peptides products, IGF-1 LR3, and steroids and SARMs products, EGF, VEGF etc., in China. All the managers and engineers are experts in the fields of biology, chemistry, or pharmaceutics. They have been engaged in these kinds of products for many years.

Our company strictly compliance with the GMP standards , we have the most advanced production equipment and technology reserves. our products has been exporting to the overseas market such as U.S.A., Europe, etc. for many years.All our clients speak highly of our high quality products and professional services.

We are always paying much more attention to quality assurance and quality control. As an innovative team, our proposals always fit customer’s requirements. As a cooperative team, we always devote better services to our customers.

Get Latest Price For Your Requirement
PRODUCT DESCRIPTION
High Light:

hgh growth factor

,

igf muscle growth

Place of Origin China
Brand Name SGH
Certification GMP, ISO9001,BRC,KOSHER
Model Number IGF-1 DES
Minimum Order Quantity 10vials (1kit)
Price Negotiation
Packaging Details Discreet package or foiled bag or pack as customer's request
Payment Terms T/T, Western Union, MoneyGram, Bitcoin
Supply Ability 10000vials/Month
Synonyms DES
Size 1mg/vial
Form Lyophilized powder
Usage Bodybuilding
Color White
Storage -20C

 

Muscle Building IGF Peptide IGF-1 DES 1mg/vial Growth Hormone For Weight Loss

Description:

Cas No. N/A

Synonyms: IGF-1 DES

MW: 7371.4

Appearance: White Powder

Purity: >95%(HPLC)

Source: Chemical Synthesis

 

Sequence:

H-Thr-Leu-Cys-Gly-Ala-Glu-Leu-Val-Asp-Ala-Leu-Gln-Phe-Val-Cys-Gly-Asp-Arg-Gly-Phe-Tyr-Phe-Asn-Lys-Pro-Thr-Gly-Tyr-Gly-Ser-Ser-Ser-Arg-Arg-Ala-Pro-Gln-Thr-Gly-Ile-Val-Asp-Glu-Cys-Cys-Phe-Arg-Ser-Cys-Asp-Leu-Arg-Arg-Leu-Glu-Met-Tyr-Cys-Ala-Pro-Leu-Lys-Pro-Ala-Lys-Ser-Ala-OH

 

Purity: >95%

Bacterial Endotoxins: < 5EU/mg

 

Introduction:

 

The somatomedins, or insulin-like growth factors (IGFs), comprise a family of peptides that play important roles in mammalian growth and development. IGF-1 DES is a truncated form of IGF-1, which mediates many of the growth-promoting effects of growth hormone, with the tri-peptide structure Glycine-Proline-Glutamine cleaved from the N-terminus. It has been isolated from and detected in numerous in vivo sources, including the human brain, bovine colostrum, and porcine uterus. In vitro studies demonstrate that at equal doses DES (1-3) IGF is ten times more potent than IGF-1 at stimulating hypertrophy and proliferation in cultured cells. It is likely generated through post-translational modification in the sequence of circulating mature IGF-1 via protease action.

 

 

Insulin Like Growth Factor (IGF)-1 (4-70), otherwise known as IGF-1 DES, produced in E. coli, is a single, non-glycosylated, polypeptide chain containing 67 amino acids and having a molecular mass of 7,372 Da. In vitro studies demonstrate that at equal doses DES (1-3) IGF is ten times more potent than IGF-1 at stimulating hypertrophy and proliferation in cultured cells. It is likely generated through post-translational modification in the sequence of circulating mature IGF-1 via protease action.

IGF-1 DES is a cleaved form of IGF-1 and contains amino acids 4-70. This structure has allowed the effects of the IGF-1 protein to be amplified in the more stable form of the DES 1,3 molecule peptide protein fragment of Insulin-like growth factor 1. The IGF-1 DES, or insulin-like growth factor DES, comes from the IGF-1 family of peptides that play important roles in mammalian growth and development. IGF1 mediates many of the growth-promoting effects of growth hormone and IGF-1 DES, although shorter, pacts an equal amount of physiological altering protein physical changes. Early studies showed that growth hormone did not directly stimulate the incorporation of sulfate into cartilage, but rather acted through a serum factor, termed 'sulfation factor,' which later became known as 'somatomedin' or IGF-1 and more recently through truncation, DES IGF-1.

 

 

The efficacy of insulin-like growth factor I (IGF-I) in enhancing growth in animals with reduced renal mass was investigated in subtotally nephrectomized young male rats. Recombinant human IGF-I was administered by osmotic minipumps for 7 days at two doses, 0.9 and 2.2 mg.kg body wt-1. day-1, and the truncated analogue of IGF-I, des-(1-3)IGF-I, was given at a dose of 0.9 mg.kg body wt-1.day-1. The partial nephrectomy procedure resulted in significantly impaired renal function as evidenced by elevated serum urea and creatinine concentrations, reduced creatinine clearance, and increased average daily urine output. Carcass composition was significantly altered in animals with reduced renal mass; water content increased and fat content decreased, while protein content remained unchanged. Carcass composition was not affected by IGF treatment. Body weight gain, food utilization, and nitrogen balance during the treatment period were significantly increased in rats treated with IGF-I at both the lower and higher doses and in those treated with des-(1-3)IGF-I. The improved nitrogen balance in the des-(1-3)IGF-I group could at least partly be explained by a diminished rate of muscle protein breakdown, as indicated by the reduced urinary excretion rate of 3-methylhistidine. Compensatory hypertrophy of the remnant kidney was significantly increased in the group treated with the high dose of IGF-I. These results suggest that IGF-I may have beneficial effects on somatic growth and nitrogen balance in renal insufficiency, with des-(1--3)IGF-I being particularly effective in reducing the rate of muscle protein breakdown.

 

 

 

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